by and large - translation to English
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by and large - translation to English

BRITISH COMEDY DOUBLE ACT
Little and large; The Little and Large Party

by and large      
= en general, en gran medida
Ex: This has been the case with newspapers which by and large have changed very little over the past century.
by and large      
en general
by and by         
CHRISTIAN SONG
By And By
más tarde, luego

Definition

bypass
bypass (ingl.; pronunc. [baipás]; pl. "bypass" o "bypasses", pronunc. [baipás] o [baipáses]) m. Med. Intervención quirúrgica que tiene por objeto restablecer el flujo sanguíneo en una arteria dañada.

Wikipedia

Little and Large

Little and Large were a British comedy double act comprising straight man Syd Little (born Cyril John Mead; 19 December 1942) and comic Eddie Large (born Edward Hugh McGinnis; 25 June 1941 – 2 April 2020).

Examples of use of by and large
1. Locals here are, by and large, proud to play host.
2. But those buyers, by and large, aren‘t showing up.
3. By and large trade volumes have remained high," he said.
4. By and large, he introduced the Macleod–Cockfield reforms.
5. "That‘s by and large now the preserve of the wealthy.